The Food and Drug Administration is investigating whether the brand Crestor, sold under the brand name Crestor, could be more effective than competitors on a broader scale in reducing cardiovascular disease. The drug, which is prescribed for patients with high cholesterol, is approved for use by the FDA in adults and by the elderly, according to the agency's.
Crestor, also known as rosuvastatin, is the brand name for Crestor, an atorvastatin calcium calcium, a statin that is widely prescribed for high cholesterol.
The FDA has approved Crestor to treat patients with high cholesterol, but it was also approved for a different class of medications called "statins," which are drugs that lower cholesterol and reduce the risk of heart disease. Other statins, such as simvastatin and atorvastatin, are approved for a different indication.
"As with statins, statin drugs can be more expensive than their counterparts," said Dr. Lisa D. Geller, a leading clinical endocrinologist at Brigham and Women's Hospital in Boston, who was not involved in the study.
Crestor is one of a number of generic prescription drug forms, including Zocor, which is sold by Teva Pharmaceuticals. Zocor, a generic version of Lipitor, is also approved by the FDA for the treatment of high cholesterol.
The Food and Drug Administration has been investigating whether Crestor can be more effective than Zocor in reducing the risk of heart disease, but the agency hasn't approved it.
"The results of this study are in line with the results of previous studies that have suggested a potential benefit to the cardiovascular system for Crestor," Geller said.
The FDA also hasn't made a clear decision on whether Crestor could have other cardiovascular benefits, Geller said.
While the FDA's approval of Crestor to treat patients with high cholesterol, which is the most common cause of death in the United States, is a step in the right direction, the agency's clinical research and the results of clinical studies have been mixed.
One study that Geller and her team conducted looked at the safety of Crestor in patients with high cholesterol. They found that patients with higher cholesterol levels had a significantly lower risk of death compared to patients with low levels.
Geller said that while the results of the study may be reassuring, she was cautious about the risk-benefit assessment given the limited data on Crestor.
In an accompanying editorial in theNew England Journal of Medicine, Dr. Elizabeth Hargroves, the lead investigator of the study, said: "The results of the study do not support the use of statins in patients with high cholesterol, and they do not support the use of Crestor in patients with low cholesterol."
The results of the study also suggest that statins, even in the form of generic Crestor, could be effective at reducing the risk of heart disease in patients with high cholesterol, Geller said. The risk of heart attack and stroke was reduced by 80 percent and 90 percent, respectively, in patients with high cholesterol.
Crestor is currently in phase 2 clinical studies for the treatment of patients with high cholesterol, Geller said.
"This study demonstrates that Crestor, in addition to being a highly effective statin, is not superior to other currently available statin drugs," said Dr. Michael O'Leary, the lead investigator of the study and a professor of endocrinology at the University of Rochester Medical Center.
The study is the first to evaluate the long-term safety and efficacy of Crestor for patients with high cholesterol, Geller said.
"We found that patients with high cholesterol levels were more likely to have an increased risk of cardiovascular disease, such as heart disease, and to have a higher risk of dying from cardiovascular events in the study," Geller said.
The FDA has not approved Crestor for use in patients with a history of heart disease, and the study was stopped earlier this week after the company's clinical trials for the drug failed to show a significant benefit from Crestor.
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In the U. S., AstraZeneca was one of the first to offer AstraZeneca discount coupons in 2014, a record high. The company’s 2016 acquisition of Novartis made it the first in the global market to offer AstraZeneca the global discount coupon, including savings on brand name drugs. The company had previously been offering AstraZeneca savings on generics, but now is offering a 90-day supply.
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CRESTOR 10MG TABLET is used in the management of high blood cholesterol levels. It is prescribed when diet and exercise does not result in adequate results. It contains a medicine called which is an anti-hyperlipidemic agent that works by blocking cholesterol production in the body. It also makes your body eliminate lipids particles from the blood.
By reducing blood cholesterol levels, this medicine is helpful is reducing cardiovascular risks and problems in blood circulation across the body. While taking CRESTOR 10MG TABLET, you must follow a cholesterol-lowering diet, lifestyle changes and regular physical activity as instructed by your doctor to achieve better results.
Before taking CRESTOR 10MG TABLET inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have diabetes, thyroid problems, or a family history of muscle disorders. Do not take CRESTOR 10MG TABLET if you are pregnant or breastfeeding without consulting your doctor.
CRESTOR 10MG TABLET may increase your blood sugar levels, especially in patients who are diabetic. It may also affect the way your liver works and so your doctor will closely monitor your blood sugar levels and liver functions while undergoing therapy with CRESTOR 10MG TABLET as a precaution.
The most common side effects of taking CRESTOR 10MG TABLET are muscle ache, constipation, stomach pain, dizziness, nausea and headache. Inform your doctor if you experience severe unexplained muscle pain, tenderness or weakness along with fever after taking CRESTOR 10MG TABLET.
How should I take CRESTOR 10MG TABLET? CRESTOR 10MG TABLET should be taken only when needed. It should be taken 5-10 times daily, every 5 years, as needed. It should be taken with caution in patients with breathing problems. The dose should be taken at least 10 minutes before the activity and for at least 10 minutes after the activity. The dosage of CRESTOR 10MG TABLET may need to be adjusted depending on the patient’s cholesterol levels.The side effects of CRESTOR 10MG TABLET are similar to those of other hyperlipoproteinemongly 20 mg tabletares. However, there are some potential side effects that may occur. Here’s a brief guide about some of the most common side effects of CRESTOR 10MG TABLET:
Some of the most commonly reported side effects of taking CRESTOR 10MG TABLET may include:
Sharma may change the dose of CRESTOR 10MG TABLET or in the case of an adverse reaction, be advised to increase the dosage to 10 mg or decrease to 1 mg. The most common side effects of taking CRESTOR 10MG TABLET are as follows:
No, not if you are not using probenecid based diet or exercise.
You should inform your doctor before taking CRESTOR 10MG TABLET if you are pregnant or breastfeeding any. It may be prescribed to you to reduce the blood sugar levels in the first place. If you become pregnant, think you or your doctor may take CRESTOR 10MG TABLET, stop taking it and contact your doctor withoutFIDABLE doctors advice.
When and if will I take CRESTOR 10MG TABLET again? Before taking CRESTOR 10MG TABLET, you must first tell your doctor if you have any or problems with your heart, liver, kidney or heart rhythm.₹110Original price was: ₹110.99.88Current price is: ₹88.99.arious.
CRESTOR 40MG TABLET is a medicine that helps to reduce high blood pressure in the body. It is commonly used to treat conditions related to high blood pressure and high cholesterol.
CRESTOR 40MG TABLET contains the active ingredient Rosuvastatin which belongs to the group of medicines known as HMG-CoA reductase inhibitors. This medicine can help to reduce the risk of serious problems like strokes, heart attacks, and blood clots. It works by inhibiting the enzyme HMG-CoA reductase which is responsible for breaking down cholesterol in the body. High blood cholesterol is the main reason for high blood pressure and heart disease. Lowering the levels of cholesterol can help to lower the risk of heart diseases like stroke, heart attacks, and blood clots.
Take it regularly as prescribed by your doctor. In case you forget to take your dose, take it as soon as you remember it. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at the same time.
Do not take this medicine for more than one year even if you already have high blood pressure or liver problems. It may lead to serious side effects like dizziness, drowsiness, fatigue, nausea, vomiting, and sleepiness.
It may also cause heart problems like irregular heartbeat, chest pain, and trouble breathing. So it is important to keep taking it until the end of the year. If you have any doubts about this medicine, consult your doctor.
Read more about CrestorCRESTOR 40MG TABLET is a medicine that helps to reduce the high blood pressure in the body.
Read more aboutCRESTOR 40MG TABLET works by inhibiting the action of an enzyme called HMG-CoA reductase which is involved in the breakdown of cholesterol in the body. The reduction in cholesterol levels leads to the accumulation of cholesterol in the blood and can cause the symptoms like dizziness, fatigue, dry mouth, and weakness.
CRESTORIt helps to lower the risk of serious problems like strokes, heart attacks, and blood clots.
CRESTOR 40MG TABLET is used to lower the levels of cholesterol in the blood.
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